Green book seasonal influenza mortality

How deadly is covid19 compared to the seasonal flu. Estimates of global seasonal influenzaassociated respiratory mortality. Not recommended for use as part of seasonal influenza vaccination. Take the 20192020 seasonal influenza vaccination training. Death rates estimated by the cdc range from about 12,000 during 20112012 to 56,000 during 201220. Seasonal influenza is a preventable infectious disease with mostly respiratory symptoms. Influenza flu is a respiratory illness caused by influenza viruses. Apr 11, 2016 influenza activity started in week 502014 and lasted until week 202015, as in the previous season. Cdc influenza surveillance data confirms severity of flu. The french data were obtained from the sentinel system, created in 1984.

It is caused by influenza virus and is easily transmitted, predominantly via the droplet and contact routes and by indirect spread from respiratory secretions on hands etc. Modelling the population effectiveness of the national. In hong kong, seasonal influenza is usually more common in periods from january to marchapril and from july to august. The exact burden of influenza is difficult to quantify because laboratory tests are rarely conducted on a routine basis. Estimates of global seasonal influenzaassociated respiratory. Seasonal influenza epidemics have a substantial mortality and morbidity impact on human health globally.

Elderly people, children under 6 months old, pregnant women, and people with chronic conditions or immunosuppression are at increased risk of complications. Influenza, commonly known as the flu, is an infectious disease caused by an influenza virus. Seasonality of mortality, by kyle nobbe, published in the january 2017 edition of reflections, 1 and seasonal flu and the impact on mortality, by dr. For information on the use of influenza vaccines in egg allergic individuals please see the green book influenza. More information about clinical risk groups and vaccination can be found in the influenza green book chapter 19 and nice national institute for health and care excellence guidance. The severity of seasonal influenza depends on the virus, host. Green book 3 and in the annual flu letter for 2018192. Previous global influenza mortality estimates were calculated more than 10 years ago and detailed information about the methods used are not available.

Influenza april 2019 19 influenza the disease influenza is an acute viral infection of the respiratory tract. Influenza is an acute viral infection of the respiratory tract that spreads easily from person to person. Inactivated influenza vaccine information for healthcare. Based on national center for health statistics nchs mortality surveillance data available on may 14, 2020, 8. Influenza vaccination for immunocompromised patients. Pdf mortality burden from seasonal influenza and 2009. Seasonal influenza annual epidemiological report for 2014. Mortality is only the most severe manifestation of influenza impact, and similar techniques can be used to estimate excess morbidity due to influenza epidemics. Compared with the previous season, nine eueea countries reported higher peak ili rates in primary care. For a variety of pandemic influenza scenarios attack rate 20% or. With news circulating that influenza kills more people, the world health organisation.

The current recommendations for seasonal influenza vaccine in the influenza chapter of the green book. Seasonal influenza is a common respiratory tract infection caused by human seasonal influenza viruses. Mortality associated with influenza and respiratory syncytial virus in. In contrast, avian influenza ai is caused by those influenza viruses that mainly affect birds and.

A new study from harvard university found that the death rate on the diamond princess ship was 0. History of 1918 flu pandemic pandemic influenza flu cdc. This percentage is above the epidemic threshold of 6. Influenza is an acute viral infection of the respiratory tract. No elevated risk was found for cancer, infections, neurodevelopmental problems, chronic diseases, or all cause morbidity or mortality in the children of vaccinated mothers. Aug 27, 2010 during 19762007, annual estimates of influenza associated deaths from respiratory and circulatory causes ranged from 3,349 in 198687 to 48,614 in 200304, and the annual rate of influenza associated death for all ages ranged from 1. Because of probably vaccinations and the treatment like we have tamiflu and medications, the mortality is not that high with the seasonal flu probably 0. It is totally different from avian influenza and influenza pandemic. Coronavirus is five times deadlier than the seasonal flu. The mdhhs seasonal influenza web page has information on influenza activity, influenza vaccination, and resources for specific groups including health professionals and clinical laboratories. Several studies have shown a relatively high mortality rate among young people infected by the 2009 pandemic influenza a h1n1 virus. For the latest influenza surveillance data, click the image below. Excess mortality was 36 fold higher during seasons dominated by the ah3n2 subtype than seasons dominated by ah1n1b. In 2000, the policy was extended to include all people aged.

Uk with an overall estimated case fatality ratio of. Impact of influenza vaccination on seasonal mortality in the. Influenza medicago announces positive results in animal trials for its vaccine candidate against covid19. Influenza a and influenza b are responsible for most clinical illness. Influenza types a and b are responsible for most cases of clinical illness in the uk. Annual national flu programme letter 2019 to 2020 nhs england. The purpose of the influenza vaccination programme is to protect those most at risk of developing severe disease or complications or from dying if they develop the infection. The mortality rate associated with the 2009 h1n1 pandemic in 200910 was comparable to that of seasonal influenza during the seasonal years 19. New evidence emerged following the 2009 h1n1 influenza pandemic that obesity was an independent risk factor for hospitalization, intensive care unit admission and death in laboratory. Impact of influenza vaccination on seasonal mortality in. Note the flu information page below can be slow to load, please be patient, it is loading the latest information. Clinical practice guidelines by the infectious diseases. Influenza is highly infectious with a usual incubation period of one to three days. The influenza chapter in the green book contains more details of the clinical and.

Seasonal influenza an overview sciencedirect topics. Estimates of deaths associated with seasonal influenza. The most recent data for the mortality death rates from influenza rate death rate for the united states in 2016 indicates that mortality from influenza varies from year to year. For deaths with underlying pneumonia and influenza causes during 19762007 in the united states, the models estimated an annual. The latter is a nationwide network of general practitioners who report, in real time, the number of medical visits. Overall influenzaassociated mortality has been estimated to. The net result is a resounding lack of evidence of harm from flu vaccination in pregnancy. Comparative age distribution of influenza morbidity and. Here we compared the age distributions of morbidity and mortality during two seasonal influenza epidemics h1n1 and h3n2 in france and the united states with those of the 2009 h1n1 pandemic waves in the same countries. Vaccines for the prevention of seasonal influenza in patients. Mortality attributable to seasonal and pandemic influenza. Influenza immunisation has been recommended in the uk since the late 1960s, with the aim of directly protecting those in clinical risk groups who are at a higher risk of influenza associated morbidity and mortality. Jun 30, 2017 large variation in estimates was observed among studies. Inactivated influenza vaccine information for healthcare practioners.

Influenza a occurs more frequently and is more virulent. During the pandemic, there were fewer than 500 laboratory confirmed deaths from influenza ah1n1v in the. Morbidity and mortality attributed to flu is a key factor in hsc winter pressures and a. We chose influenzalike illness ili as the sole indicator of morbidity. Influenza activity can sometimes be predicted and even tracked geographically. Variations in influenzaassociated mortality by age group also should be noted. Number of fatal flu cases % mortality rate per 100,000 population ageadjusted relative risk in a risk group. In the united states, it was first identified in military personnel in spring 1918.

We believe this further increases the likelihood that the singular cause of excess winter seasonal mortality is, in fact, influenza. Budd said influenza a h3n2 is the predominant strain of the virus this season, which is often linked with higher mortality and hospitalization rates among older adults and young children, though. Influenza and the winter increase in mortality in the. The annual crude influenza associated allcause mortality rate for all ages, subdivided by period, ranged from 0 to 178 per 100,000 persons in seasonal periods. The michigan department of health and human services mdhhs seasonal influenza is a contagious respiratory illness caused by influenza viruses. Influenza is an acute respiratory viral infection which typically occurs in the winter months in temperate areas. The us centers for disease control and prevention cdc documented that seasonal influenza was responsible for 34,40057,300 deaths during the 20182019 season. A, in the unadjusted findings, the black circles show the 3year moving averages of the excess mortality rates, and the green line shows influenza vaccination coverage. In the northern hemisphere, cases of influenza occur in greater numbers during the winter months, usually peaking from december to march, with a 5% to 20% attack rate in the general population. Influenza was associated with a seasonal average of 24. Vol 391 march 31, 2018 1285 estimates of global seasonal influenzaassociated respiratory mortality. Public health england phe reports that morbidity and mortality attributed to flu is a major cause of harm to individuals, especially vulnerable people, and a key factor in nhs winter pressures. Investigating obesity as a risk factor for influenza.

Seasonal and pandemic influenza are well documented in producing a significant burden of morbidity and mortality on human health. Seasonal influenza vaccination programme 201819 business. Antiviral medications for pregnant women for pandemic and. Mortality is highest in infants and elderly persons. Heterogeneity in estimates of the impact of influenza on. Influenza is usually self limiting in healthy individuals, with recovery in 37 days. The 1918 influenza pandemic was the most severe pandemic in recent history. Serious outcomes can include hospitalization or death. Seasonal influenza results in yearly epidemics of varying severity, with sporadic cases or outbreaks occurring outside of typical season patterns. Influenza types a and b are responsible for most cases of clinical illness in. Inactivated influenza vaccine information for healthcare practitioners. For seasonal influenza, mortality is usually well below 0. Furthermore, exacerbations of underlying disease, e. This guideline will also be used to develop the nice quality standard for flu.

Several studies have suggested that respiratory pathogens other than influenza viruses, especially respiratory syncytial virus, contribute to. Since these estimates were made available by who the number of countries with capacity to calculate national estimates for seasonal influenzaassociated excess mortality has increased. You also see that the age of the children is variable. Although there is not universal consensus regarding where the virus originated, it spread worldwide during 19181919.

While the beginning of major flu activity in each season varies by location, in any. Excess mortality associated with influenza epidemics in. Patients with reduced immune function due to disease or pharmacotherapy are vulnerable to severe or complicated influenza infection, and national immunisation guidelines commonly recommend this population are vaccinated to protect against such outcomes. Flu season is an annually recurring time period characterized by the prevalence of outbreaks of influenza flu. Since these estimates were made available by who the number of countries with capacity to calculate national estimates for seasonal influenza associated excess mortality has increased. Influenza causes significant loss of workdays, human suffering, and mortality.

Influenza chapter 19 influenza april 2019 table 19. These clinical practice guidelines are an update of the guidelines published by the infectious diseases society of america idsa in 2009, prior to the 2009 h1n1 influenza pandemic. Prevention and control of seasonal influenza with vaccines recommendations of the advisory committee on immunization practices united states, 201617 influenza season. Influenza or flu leads to the hospitalization of more than 200,000 people yearly and results in 36,000 deaths from flu or flurelated complications in the united states 15, striking both the elderly and infant populations particularly hard 24. Influenza is a highly infectious, viral infection of the respiratory tract. The influenza chapter of the green book recommends both intradermal and. In almost all countries, the season was dominated by influenza ah3n2 viruses. High excess mortality impact was also seen in children. Every winter, the uk experiences a seasonal influenza epidemic that affects the morbidity and mortality of thousands of its citizens and puts increased pressure on nhs resources. These symptoms typically begin two days after exposure to the virus and most last less than a week. Some people, such as older adults, young children, and people with certain health conditions, are at higher risk for flu complications.

Further information on influenza infection is included in the green book influenza chapter and on nhs. Immunisation against infectious disease the green book, 2014. This document addresses new information regarding diagnostic testing, treatment and chemoprophylaxis with antiviral medications, and issues related to institutional outbreak management for seasonal influenza. In the 20172018 season, deaths reached a new high of about. Epidemiological factors associated with increased odds for influenza included weeks when. The mdhhs seasonal influenza web page has information on influenza activity, influenza vaccination, and resources for specific groups including health. It was caused by an h1n1 virus with genes of avian origin. Influenza type a causes moderate to severe illness and affects all age groups. Overall influenza associated mortality has been estimated to. The cdc presents seasonal influenza morbidity and mortality not as raw numbers, but as calculated estimates based on submitted international. Public health england gateway number 2018805 pdf, 8kb, 27 pages this file may not be suitable for users of assistive technology. The severity of seasonal influenza depends on the virus, host factors, and other factors, e. As reported in this and other studies, 2,3 approximately 90%.

Influenza, influenzaassociated mortality, and novel. Jun 21, 2011 influenza was associated with a seasonal average of 24. Influenza a in this season was predominating so it caused 60% of the deaths, but both types of influenza a and both types of influenza b can cause mortality. The average annual number of influenzaassociated deaths during influenza ah3n2 prominent seasons was 7,722 for pneumonia and influenza causes and 28,909 for respiratory and circulatory causes, compared with 2,856 deaths for pneumonia and influenza causes and 10,648 deaths for respiratory and circulatory causes in seasons in which it was not. The season occurs during the cold half of the year in each hemisphere. Influenza vaccination and 1year risk of myocardial infarction, stroke, heart failure, pneumonia, and mortality among intensive care unit survivors aged 65 years or older. Abstract this article follows up on two older articles by rga associates. Mortality attributable to seasonal and pandemic influenza, australia, 2003 to 2009, using a novel time series smoothing approach article pdf available in plos one 86. Immunisation against infectious diseases the green book and updates. Why flu vaccination is important for health care workers hse. Influenza is an acute respiratory illness caused by rna viruses of the family orthomyxoviridae influenza viruses. Healthcare practitioners should refer to the green book influenza chapter for. Visit the 20192020 seasonal influenza resource center.

Influenza immunisation information including updates for public health professionals. The dates of the us seasonal epidemics and the age distribution of ili were extracted from published studies 8. Influenza august 2018 19 influenza the disease influenza is an acute viral infection of the respiratory tract. Flu is responsible for between 200 and 500 deaths each year in ireland. High excess mortality impact was also seen in children under the age of four years. Influenza, commonly referred to as the flu, is a severe respiratory illness that is easily spread and can lead to severe complications, even death. In diabetic patients of workingage 1864 years, influenza vaccination prevented allcause hospitalization with a pooled ve of 58% 95% ci, 681% and hospitalization due to influenza or pneumonia ve 43%.